Mimics of scleroderma

Scleroderma with Nodular Scleroderma

BACKGROUND Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea. A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type. Treatment is challenging, and several treatments modalities have been reported with unsatisfactory results. MAIN OBSERVATIONS We present a case of systemic scleros...

When is scleroderma really scleroderma?

Scleroderma.

The prototypic autoimmune diseases involving skin (lupus, dermatomyositis) typically result in epithelial injury and autoantibodies to characteristic cellular antigens. Disease-specific autoantibodies are also found in scleroderma, but scleroderma is different from other cutaneous autoimmune diseases because epithelial injury does not occur. Multiple factors and combinations of factors (immune ...

Stroke mimics in patients with clinical signs of stroke

Background: Stroke mimic is a major diagnostic challenge and may be difficult to distinguish from real strokes. The aim of this study was to evaluate the relative frequency of stroke mimics in patients with clinical signs of stroke. Methods: In this cross sectional-study, the medical records of 1985 patients with stroke admitted to Poursina Hospital were enrolled using the census technique. ...

Intriguing presentation of scleroderma renal crisis (scleroderma renal crisis sine scleroderma sine hypertension).

Key words: systemic sclerosis; scleroderma renal crisis; to complain of arthralgia affecting mainly her wrists sine scleroderma; sine hypertension and small joints of the hands. For the last several months she had experienced difficulty in swallowing and anorexia with a resultant weight loss of 20 kg. Despite these symptoms, she did not seek medical